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Human Protein Atlas d immunofluorescence images
Expression pattern and diagnostic value of IFI30 in stomach adenocarcinoma (STAD). A Pan-cancer integrated analysis of TCGA and GTEx datasets showing significantly elevated IFI30 mRNA levels in STAD tissues compared with normal gastric tissues. B Paired-sample analysis from the TCGA cohort confirming consistently higher IFI30 expression in gastric cancer tissues relative to matched adjacent normal tissues. C Multi-tissue heat-map visualization based on the pan-cancer TCGA-GTEx database demonstrates up-regulation of IFI30 across gastrointestinal and immune-related malignancies, with the most pronounced elevation in STAD. D <t>Immunofluorescence</t> images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization. E Analysis of the TCGA dataset showing significantly higher IFI30 expression in gastric cancer tissues versus normal gastric tissues, validated by paired-sample analysis; receiver operating characteristic (ROC) curve analysis demonstrating strong diagnostic performance of IFI30 expression for distinguishing STAD from normal gastric tissues (AUC = 0.92; 95% CI: 0.89–0.95). Statistical significance: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
D Immunofluorescence Images, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "Copy-number amplification drives IFI30 overexpression and coordinated immune activation, identifying a novel diagnostic and therapeutic target in gastric adenocarcinoma"

Article Title: Copy-number amplification drives IFI30 overexpression and coordinated immune activation, identifying a novel diagnostic and therapeutic target in gastric adenocarcinoma

Journal: Scientific Reports

doi: 10.1038/s41598-026-37574-z

Expression pattern and diagnostic value of IFI30 in stomach adenocarcinoma (STAD). A Pan-cancer integrated analysis of TCGA and GTEx datasets showing significantly elevated IFI30 mRNA levels in STAD tissues compared with normal gastric tissues. B Paired-sample analysis from the TCGA cohort confirming consistently higher IFI30 expression in gastric cancer tissues relative to matched adjacent normal tissues. C Multi-tissue heat-map visualization based on the pan-cancer TCGA-GTEx database demonstrates up-regulation of IFI30 across gastrointestinal and immune-related malignancies, with the most pronounced elevation in STAD. D Immunofluorescence images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization. E Analysis of the TCGA dataset showing significantly higher IFI30 expression in gastric cancer tissues versus normal gastric tissues, validated by paired-sample analysis; receiver operating characteristic (ROC) curve analysis demonstrating strong diagnostic performance of IFI30 expression for distinguishing STAD from normal gastric tissues (AUC = 0.92; 95% CI: 0.89–0.95). Statistical significance: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
Figure Legend Snippet: Expression pattern and diagnostic value of IFI30 in stomach adenocarcinoma (STAD). A Pan-cancer integrated analysis of TCGA and GTEx datasets showing significantly elevated IFI30 mRNA levels in STAD tissues compared with normal gastric tissues. B Paired-sample analysis from the TCGA cohort confirming consistently higher IFI30 expression in gastric cancer tissues relative to matched adjacent normal tissues. C Multi-tissue heat-map visualization based on the pan-cancer TCGA-GTEx database demonstrates up-regulation of IFI30 across gastrointestinal and immune-related malignancies, with the most pronounced elevation in STAD. D Immunofluorescence images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization. E Analysis of the TCGA dataset showing significantly higher IFI30 expression in gastric cancer tissues versus normal gastric tissues, validated by paired-sample analysis; receiver operating characteristic (ROC) curve analysis demonstrating strong diagnostic performance of IFI30 expression for distinguishing STAD from normal gastric tissues (AUC = 0.92; 95% CI: 0.89–0.95). Statistical significance: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

Techniques Used: Expressing, Diagnostic Assay, Immunofluorescence



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Expression pattern and diagnostic value of IFI30 in stomach adenocarcinoma (STAD). A Pan-cancer integrated analysis of TCGA and GTEx datasets showing significantly elevated IFI30 mRNA levels in STAD tissues compared with normal gastric tissues. B Paired-sample analysis from the TCGA cohort confirming consistently higher IFI30 expression in gastric cancer tissues relative to matched adjacent normal tissues. C Multi-tissue heat-map visualization based on the pan-cancer TCGA-GTEx database demonstrates up-regulation of IFI30 across gastrointestinal and immune-related malignancies, with the most pronounced elevation in STAD. D <t>Immunofluorescence</t> images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization. E Analysis of the TCGA dataset showing significantly higher IFI30 expression in gastric cancer tissues versus normal gastric tissues, validated by paired-sample analysis; receiver operating characteristic (ROC) curve analysis demonstrating strong diagnostic performance of IFI30 expression for distinguishing STAD from normal gastric tissues (AUC = 0.92; 95% CI: 0.89–0.95). Statistical significance: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
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Expression pattern and diagnostic value of IFI30 in stomach adenocarcinoma (STAD). A Pan-cancer integrated analysis of TCGA and GTEx datasets showing significantly elevated IFI30 mRNA levels in STAD tissues compared with normal gastric tissues. B Paired-sample analysis from the TCGA cohort confirming consistently higher IFI30 expression in gastric cancer tissues relative to matched adjacent normal tissues. C Multi-tissue heat-map visualization based on the pan-cancer TCGA-GTEx database demonstrates up-regulation of IFI30 across gastrointestinal and immune-related malignancies, with the most pronounced elevation in STAD. D <t>Immunofluorescence</t> images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization. E Analysis of the TCGA dataset showing significantly higher IFI30 expression in gastric cancer tissues versus normal gastric tissues, validated by paired-sample analysis; receiver operating characteristic (ROC) curve analysis demonstrating strong diagnostic performance of IFI30 expression for distinguishing STAD from normal gastric tissues (AUC = 0.92; 95% CI: 0.89–0.95). Statistical significance: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
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Expression pattern and diagnostic value of IFI30 in stomach adenocarcinoma (STAD). A Pan-cancer integrated analysis of TCGA and GTEx datasets showing significantly elevated IFI30 mRNA levels in STAD tissues compared with normal gastric tissues. B Paired-sample analysis from the TCGA cohort confirming consistently higher IFI30 expression in gastric cancer tissues relative to matched adjacent normal tissues. C Multi-tissue heat-map visualization based on the pan-cancer TCGA-GTEx database demonstrates up-regulation of IFI30 across gastrointestinal and immune-related malignancies, with the most pronounced elevation in STAD. D <t>Immunofluorescence</t> images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization. E Analysis of the TCGA dataset showing significantly higher IFI30 expression in gastric cancer tissues versus normal gastric tissues, validated by paired-sample analysis; receiver operating characteristic (ROC) curve analysis demonstrating strong diagnostic performance of IFI30 expression for distinguishing STAD from normal gastric tissues (AUC = 0.92; 95% CI: 0.89–0.95). Statistical significance: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
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Expression pattern and diagnostic value of IFI30 in stomach adenocarcinoma (STAD). A Pan-cancer integrated analysis of TCGA and GTEx datasets showing significantly elevated IFI30 mRNA levels in STAD tissues compared with normal gastric tissues. B Paired-sample analysis from the TCGA cohort confirming consistently higher IFI30 expression in gastric cancer tissues relative to matched adjacent normal tissues. C Multi-tissue heat-map visualization based on the pan-cancer TCGA-GTEx database demonstrates up-regulation of IFI30 across gastrointestinal and immune-related malignancies, with the most pronounced elevation in STAD. D <t>Immunofluorescence</t> images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization. E Analysis of the TCGA dataset showing significantly higher IFI30 expression in gastric cancer tissues versus normal gastric tissues, validated by paired-sample analysis; receiver operating characteristic (ROC) curve analysis demonstrating strong diagnostic performance of IFI30 expression for distinguishing STAD from normal gastric tissues (AUC = 0.92; 95% CI: 0.89–0.95). Statistical significance: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
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Image Search Results


Expression pattern and diagnostic value of IFI30 in stomach adenocarcinoma (STAD). A Pan-cancer integrated analysis of TCGA and GTEx datasets showing significantly elevated IFI30 mRNA levels in STAD tissues compared with normal gastric tissues. B Paired-sample analysis from the TCGA cohort confirming consistently higher IFI30 expression in gastric cancer tissues relative to matched adjacent normal tissues. C Multi-tissue heat-map visualization based on the pan-cancer TCGA-GTEx database demonstrates up-regulation of IFI30 across gastrointestinal and immune-related malignancies, with the most pronounced elevation in STAD. D Immunofluorescence images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization. E Analysis of the TCGA dataset showing significantly higher IFI30 expression in gastric cancer tissues versus normal gastric tissues, validated by paired-sample analysis; receiver operating characteristic (ROC) curve analysis demonstrating strong diagnostic performance of IFI30 expression for distinguishing STAD from normal gastric tissues (AUC = 0.92; 95% CI: 0.89–0.95). Statistical significance: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

Journal: Scientific Reports

Article Title: Copy-number amplification drives IFI30 overexpression and coordinated immune activation, identifying a novel diagnostic and therapeutic target in gastric adenocarcinoma

doi: 10.1038/s41598-026-37574-z

Figure Lengend Snippet: Expression pattern and diagnostic value of IFI30 in stomach adenocarcinoma (STAD). A Pan-cancer integrated analysis of TCGA and GTEx datasets showing significantly elevated IFI30 mRNA levels in STAD tissues compared with normal gastric tissues. B Paired-sample analysis from the TCGA cohort confirming consistently higher IFI30 expression in gastric cancer tissues relative to matched adjacent normal tissues. C Multi-tissue heat-map visualization based on the pan-cancer TCGA-GTEx database demonstrates up-regulation of IFI30 across gastrointestinal and immune-related malignancies, with the most pronounced elevation in STAD. D Immunofluorescence images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization. E Analysis of the TCGA dataset showing significantly higher IFI30 expression in gastric cancer tissues versus normal gastric tissues, validated by paired-sample analysis; receiver operating characteristic (ROC) curve analysis demonstrating strong diagnostic performance of IFI30 expression for distinguishing STAD from normal gastric tissues (AUC = 0.92; 95% CI: 0.89–0.95). Statistical significance: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

Article Snippet: D Immunofluorescence images from the Human Protein Atlas (HPA) showing robust colocalization of IFI30 with the endoplasmic reticulum (ER), indicating its predominant ER–lysosomal subcellular localization.

Techniques: Expressing, Diagnostic Assay, Immunofluorescence